Title of article
Mono-6-(O-2,4,6-triisopropylbenzenesulfonyl)-γ-cyclodextrin, a novel intermediate for the synthesis of mono-functionalised γ-cyclodextrins
Author/Authors
Palin، نويسنده , , Ronald and Grove، نويسنده , , Simon J.A and Prosser، نويسنده , , Alan B and Zhang، نويسنده , , Ming-Qiang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
3
From page
8897
To page
8899
Abstract
A reaction between γ-cyclodextrin (γ-CD) and 2,4,6-triisopropylbenzenesulfonyl chloride in pyridine gave mono-6-(O-2,4,6-triisopropylbenzenesulfonyl)-γ-cyclodextrin in good yield (∼69%) and high purity (>98%). In contrast to other sulfonylations of γ-CD, this reaction did not give di- or tri-substituted side products and is thus useful for preparing pure mono-substituted γ-CD derivatives.
Keywords
?-Cyclodextrins , mono-substitution , Sulfonation
Journal title
Tetrahedron Letters
Serial Year
2001
Journal title
Tetrahedron Letters
Record number
1648676
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