Author/Authors :
Zeni، نويسنده , , Gilson and Lüdtke، نويسنده , , Diogo S and Nogueira، نويسنده , , Cristina W and Panatieri، نويسنده , , Rodrigo B and Braga، نويسنده , , Antônio C.F. da Silveira، نويسنده , , Claudio C and Stefani، نويسنده , , Hélio Olympio da Rocha، نويسنده , , Joao B.T. Rocha، نويسنده ,
Abstract :
A series of acetylenic furan derivatives have been synthesized via Pd-catalyzed coupling reactions of 2-(alkyltelluro)furan with several terminal alkynes. These compounds showed good anti-inflammatory activity in the carrageenin-induced rat paw edema assay. This represents a new and efficient method for the synthesis of pharmacologically active compounds.
