• Title of article

    Synthesis of 3-alkoxycarbonyl-1β-methylcarbapenem using palladium-catalyzed amidation of vinyl halide

  • Author/Authors

    Kozawa، نويسنده , , Yuji and Mori، نويسنده , , Miwako، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    111
  • To page
    114
  • Abstract
    3-Alkoxycarbonyl-1β-methylcarbapenem could be synthesized using a palladium-catalyzed CN bond-forming reaction. In this reaction, the use of Pd(OAc)2 and DPEphos gave a good result, and generation of Pd(0) in the absence of a base is necessary to increase the yield.
  • Keywords
    ?-Lactam , Carbapenem , 3-alkoxycarbonyl-1?-methylcarbapenem , palladium-catalyzed amidation , palladium-catalyzed cyclization
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1649059