Title of article
Synthesis of 3-alkoxycarbonyl-1β-methylcarbapenem using palladium-catalyzed amidation of vinyl halide
Author/Authors
Kozawa، نويسنده , , Yuji and Mori، نويسنده , , Miwako، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
111
To page
114
Abstract
3-Alkoxycarbonyl-1β-methylcarbapenem could be synthesized using a palladium-catalyzed CN bond-forming reaction. In this reaction, the use of Pd(OAc)2 and DPEphos gave a good result, and generation of Pd(0) in the absence of a base is necessary to increase the yield.
Keywords
?-Lactam , Carbapenem , 3-alkoxycarbonyl-1?-methylcarbapenem , palladium-catalyzed amidation , palladium-catalyzed cyclization
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649059
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