Erectones A and B, two dome-shaped polyprenylated phloroglucinol derivatives, from Hypericum erectum

Examination of the whole plant of the Chinese herbal medicine Hypericum erectum yielded two novel metabolites, erectones A and B (1 and 2), which were characterized by their 2,2a,3,3a,6,6a,8b,8c-octahydro-1-oxa-cyclopenta[bc]acenaphthylen-7-one cores with isoprenyl and geranyl substituents. Their structures were established using extensive spectroscopic methods.