Author/Authors :
Mehta، نويسنده , , Goverdhan and Lakshminath، نويسنده , , Sripada، نويسنده ,
Abstract :
New hydroxy azepanes with an additional hydroxymethyl side arm have been conceived and their syntheses achieved from a suitably functionalized cyclohexanoid building-block extracted from the norbornyl framework. The new iminocyclitols (homoisofagomine derivatives) exhibit weak but selective inhibitory activity in enzyme assays.