• Title of article

    Stereoselective synthesis of 22-oxacalcitriol (OCT) and analogues modified at C25

  • Author/Authors

    Fall، نويسنده , , Yagamare and Gonzلlez، نويسنده , , Victoria and Vidal، نويسنده , , Beatriz and Mouriٌo، نويسنده , , Antonio، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    427
  • To page
    429
  • Abstract
    The stereoselective synthesis of 22-oxacalcitriol (OCT) has been achieved. The triene system was introduced using the Lythgoe–Hoffmann La Roche convergent Wittig–Horner approach to couple ketoester 7 with A ring phosphine oxide 8. The value of the resulting ester 6 for synthesis of C25-modified OCT analogues is exemplified by the synthesis of 5.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1649285