Title of article
Stereoselective intramolecular Diels–Alder reactions of 3-alkenyl(oxy)-2(1H)-pyrazinones
Author/Authors
De Borggraeve، نويسنده , , Wim M. and Rombouts، نويسنده , , Frederik J.R. and Verbist، نويسنده , , Bie M.P. and Van der Eycken، نويسنده , , Erik V. and Hoornaert، نويسنده , , Georges J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
447
To page
449
Abstract
Dichloropyrazinones are reacted with alkenolates or a Grignard reagent in order to tether a dienophilic side-chain at the 3-position. The compounds smoothly undergo intramolecular Diels–Alder reaction forming tricyclic ring systems. The reactions proceed completely stereoselective yielding only endo adducts. In the case of the alkenylpyrazinone, the core skeleton of the breviamides is obtained.
Keywords
cycloaddition , Pyrazinone , Diels–Alder reaction , brevianamide
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649301
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