Title of article :
Stereoselective synthesis of (2S)-2-hydroxymethylglutamic acid, a potent agonist of metabotropic glutamate receptor mGluR3
Author/Authors :
Choudhury، نويسنده , , Prabir K and Le Nguyen، نويسنده , , Bao Khanh and Langlois، نويسنده , , Nicole، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Straightforward stereocontrolled synthesis of (2S)-2-hydroxymethylglutamic acid was achieved from (S)-pyroglutaminol, through a bicyclic silyloxypyrrole derived from the versatile unsaturated lactam 3.
Keywords :
excitatory aminoacid , stereogenic quaternary centers , silyloxypyrrole , metabotropic glutamate receptors
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
