A concise enantioselective total synthesis of rhizoxin D
Author/Authors :
Mitchell، نويسنده , , Ian S. and Pattenden، نويسنده , , Gerald and Stonehouse، نويسنده , , Jeffrey P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
5
From page :
493
To page :
497
Abstract :
A new and convergent synthesis of the antitumour macrolide rhizoxin D 2 is described. The synthesis features a Wadsworth–Emmons olefination and a facile intramolecular Stille reaction to elaborate the 16-membered macrocyclic core 5 from the vinyl iodide 3 and the vinyl stannane 4 as key steps.
