Author/Authors :
Weinmann، نويسنده , , Hilmar and Harre، نويسنده , , Michael and Koenig، نويسنده , , Klaus and Merten، نويسنده , , Erik and Tilstam، نويسنده , , Ulf، نويسنده ,
Abstract :
A new and efficient method for the preparation of 2-amino-imidazole 3 was developed. Starting from cheap commodities O-methyl-iso-urea sulphate and 2-aminoacetaldehyde-acetales the desired product is isolated through a very simple work-up in a good yield. This new procedure overcomes several technical and environmental problems of the traditional approaches to this molecule and is therefore very attractive for large-scale preparation.