Title of article
An expeditious one-pot synthesis of diethyl N-Boc-1-aminoalkylphosphonates
Author/Authors
Klepacz، نويسنده , , Anna and Zwierzak، نويسنده , , Andrzej، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
2
From page
1079
To page
1080
Abstract
A general one-pot, purification-free synthesis of diethyl N-Boc-1-aminoalkylphosphonates has been developed. The procedure involves base-catalyzed Michael-type addition of sodium diethyl phosphite to N-Boc imines generated in situ by the action of sodium hydride on α-amidoalkyl-p-tolyl sulfones in tetrahydrofuran.
Keywords
?-amidoalkyl-p-tolyl sulfones , N-BOC imines , Diethyl phosphite
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649768
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