Title of article
Microwave-enhanced Goldberg reaction: a novel route to N-arylpiperazinones and N-arylpiperazinediones
Author/Authors
Lange، نويسنده , , Jos H.M and Hofmeyer، نويسنده , , Lovina J.F and Hout، نويسنده , , Floris A.S and Osnabrug، نويسنده , , Stefan J.M and Verveer، نويسنده , , Peter C and Kruse، نويسنده , , Chris G and Feenstra، نويسنده , , Rolf W، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
1101
To page
1104
Abstract
An unprecedented microwave-enhanced Goldberg reaction constitutes the key strategic step in the synthesis of N-arylpiperazinones, N-arylpiperazinediones and N-aryl-3,4-dihydroquinolinones. Microwave irradiation greatly accelerates the Goldberg reaction using NMP as solvent. Alkylation at the 3-position of the formed N-aryl-2-piperazinones furnishes new N-aryl-3-alkyl-2-piperazinones.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1649789
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