Title of article :
Total synthesis of bengamide E
Author/Authors :
Liu، نويسنده , , Wenming and Szewczyk، نويسنده , , Joanna M and Waykole، نويسنده , , Liladhar and Repi?، نويسنده , , Oljan and Blacklock، نويسنده , , Thomas J، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
A total synthesis of bengamide E is reported. The synthesis includes the utilization of d-tartrate as the chiral building block, construction of the E-olefin by the Julia protocol, an anti-aldol reaction to generate C-2 and C-3 stereocenters, and coupling of the thioester with caprolactam hydrochloride using sodium 2-ethylhexanoate.
Keywords :
Julia olefination , bengamide E , anti-aldol , sodium 2-ethylhexanoate
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
