Title of article
Two-step solution-phase synthesis of novel quinoxalinones utilizing a UDC (Ugi/de-Boc/cyclize) strategy
Author/Authors
Nixey، نويسنده , , Thomas and Tempest، نويسنده , , Paul A. Hulme، نويسنده , , Christopher، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
1637
To page
1639
Abstract
The novel solution-phase synthesis of an array of biologically relevant quinoxalinones in a simple two-step procedure is revealed. Transformations are carried out in excellent yield by condensation of mono-Boc protected ortho-phenylene di-amine, glyoxylic acids and supporting Ugi reagents. Subsequent acid treatment and evaporation affords quinoxalinones in good to excellent yields.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650205
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