• Title of article

    O-Succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium salts as efficient reagents in active ester synthesis

  • Author/Authors

    Bailén، نويسنده , , Miguel A. and Chinchilla، نويسنده , , Rafael and Dodsworth، نويسنده , , David J and Nلjera، نويسنده , , Carmen، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    4
  • From page
    1661
  • To page
    1664
  • Abstract
    The new uronium salts O-succinimidyl-1,3-dimethyl-1,3-trimethyleneuronium hexafluorophosphate (HSDU) and tetrafluoroborate (TSDU) have been prepared from 1,3-dimethylpropyleneurea (DMPU) and employed in the synthesis of N-hydroxysuccinimide-derived active esters. High yields were obtained at room temperature in short reaction times and no racemization was observed.
  • Keywords
    amino acids , Ureas , N-hydroxysuccinimide , uronium salts , Active esters
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1650221