Author/Authors :
Gannett، نويسنده , , Peter M and Powell، نويسنده , , Jeannine H and Johnson II، نويسنده , , Edward M and Darian، نويسنده , , Eva and Dalal، نويسنده , , Naresh S and Norton، نويسنده , , Michael L and Budil، نويسنده , , David E، نويسنده ,
Abstract :
We show here that spin probe labeled oligonucleotides coupled with EPR detection can be used to detect oligonucleotide binding, to optimize conditions used for annealing, and provides a highly selective method for oligonucleotide hybridization detection under conditions that model DNA biochips.