Author/Authors :
Nampalli، نويسنده , , Satyam and Zhang، نويسنده , , Weihong and Sudhakar Rao، نويسنده , , T and Xiao، نويسنده , , Haiguang and Kotra، نويسنده , , Lakshmi P and Kumar، نويسنده , , Shiv، نويسنده ,
Abstract :
An unnatural, tri-functional amino acid, t-Boc-l-para-amino-phenylalanine (1), was utilized in the design and syntheses of highly efficient FRET cassettes (4–7) and converted them into 2′,3′-dideoxynucleotide terminators (8–11) for investigating DNA sequencing potential coupled with a thermostable DNA polymerase, Thermo Sequenase™ II.