Title of article
Synthesis and structure of 2-aryl-5,5-disubstituted-1,3-dioxanes and conversion into chiral (1,1,1-trishydroxymethyl) methane derivatives
Author/Authors
Gardiner، نويسنده , , John M and Mather، نويسنده , , Paul and Morjan، نويسنده , , Ramy and Pritchard، نويسنده , , Robin G. and Warren، نويسنده , , John E and Cooper، نويسنده , , Malcolm L and Ferwanah، نويسنده , , Abd El-Rahman S and Abu-Tiem، نويسنده , , Omar S، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2091
To page
2094
Abstract
Pentaerythritol, (1,1,1-trishydroxymethyl)methyl methane and (1,1,1-trishydroxymethyl)nitromethane are converted into 2-aryl-5,5-bis(hydroxymethyl), 2-aryl-5-hydroxymethyl-5-methyl- or 2-aryl-5-hydroxymethyl-5-nitro-1,3-dioxanes and a range of derivatives. X-Ray and NMR analysis establishes that the latter is obtained as a single diastereomer whose structure is unambiguously determined. These materials can be elaborated to chiral derivatives of the starting (1,1,1-trishydroxymethyl) methanes.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650550
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