Title of article :
Three-component synthesis of 2-haloalk-2(Z)-en-1-ols via tandem haloalkylidenation–aldehyde addition
Author/Authors :
Baati، نويسنده , , Rachid and Barma، نويسنده , , D.K. and Falck، نويسنده , , J.R. and Mioskowski، نويسنده , , Charles، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Cr(II)-induced condensation of CCl4 or CBr4 with an aldehyde stereospecifically generates an (E)-α-haloalkylidene chromium carbenoid which adds in situ to a second equivalent of aldehyde furnishing 2-haloalk-2(Z)-en-1-ols in high yield.
Keywords :
Chromium , vinylation , Alkenylation , alcohols , stereocontrol
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
