Title of article
Diastereoselective addition of metalated isoindolin-1-ones to aldehydes. Stereoselective preparation of (E)-3-arylideneisoindolin-1-ones
Author/Authors
Couture، نويسنده , , Axel and Deniau، نويسنده , , Eric and Grandclaudon، نويسنده , , Pierre and Hoarau، نويسنده , , Christophe and Rys، نويسنده , , Véronique، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
2207
To page
2210
Abstract
Lithiated isoindolinones react with aromatic aldehydes to afford 3-hydroxybenzyl derivatives with high diastereoselectivity. Dehydration of erythro and threo adducts through an E1cb mechanism gives rise indiscriminately to the (E)-arylideneisoindolinones.
Keywords
Metalation , Stereochemistry , Enamides , diastereoselection
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650627
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