Title of article :
Synthesis of cyclam-capped β-cyclodextrin-bonded silica particles for use as chiral stationary phases in capillary electrochromatography
Author/Authors :
Gong، نويسنده , , Yinhan and Xue، نويسنده , , Guoping and Xiang، نويسنده , , Yanqiao and Bradshaw، نويسنده , , Jerald S and Lee، نويسنده , , Milton L and Lee، نويسنده , , Hian Kee، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
β-Cyclodextrin (β-CD) was anchored onto silica particles at its C(2) position, derivatized primarily at the C(6) position by treatment with bromoacetyl bromide, and finally reacted with two types of cyclams to form cyclam-capped β-CD-bonded silica particles. When used as chiral stationary phases in capillary electrochromatography, these novel bonded silica particles exhibited excellent enantioselectivities for chiral separations.
Keywords :
Capillary electrochromatography , Chiral Stationary Phase , enantiomeric separation , Cyclam , Crown ether , ?-Cyclodextrin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
