Title of article :
Diastereoselective synthesis of syn-3,5-dihydroxyesters via ruthenium-catalyzed asymmetric transfer hydrogenation
Author/Authors :
Patricia Everaere، نويسنده , , Kathelyne and Franceschini، نويسنده , , Nicolas and Mortreux، نويسنده , , André C. Carpentier، نويسنده , , Jean-François، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The asymmetric transfer hydrogenation of chiral 5-hydroxy-3-ketoesters in 2-propanol using chlororuthenium(II)arene/β-amino alcohol in situ catalyst combinations or a pre-synthesized Ru-{β-amino alcohol} true catalyst, provides syn-3,5-dihydroxyesters in high yields and up to 80% de.
Keywords :
chiral Ru catalysts , Asymmetric transfer hydrogenation , syn-diols
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
