Title of article
Diastereoselective synthesis of syn-3,5-dihydroxyesters via ruthenium-catalyzed asymmetric transfer hydrogenation
Author/Authors
Patricia Everaere، نويسنده , , Kathelyne and Franceschini، نويسنده , , Nicolas and Mortreux، نويسنده , , André C. Carpentier، نويسنده , , Jean-François، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
2569
To page
2571
Abstract
The asymmetric transfer hydrogenation of chiral 5-hydroxy-3-ketoesters in 2-propanol using chlororuthenium(II)arene/β-amino alcohol in situ catalyst combinations or a pre-synthesized Ru-{β-amino alcohol} true catalyst, provides syn-3,5-dihydroxyesters in high yields and up to 80% de.
Keywords
chiral Ru catalysts , Asymmetric transfer hydrogenation , syn-diols
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650876
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