Title of article
Solution-phase parallel tetrahydrofuran synthesis with propargyl alcohols and benzylidene-(or alkylidene-)malonates
Author/Authors
Cavicchioli، نويسنده , , Marcello and Marat، نويسنده , , Xavier and Monteiro، نويسنده , , Nuno and Hartmann، نويسنده , , Beno??t and Balme، نويسنده , , Geneviève، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
2609
To page
2611
Abstract
A large array of 3-methylene tetrahydrofurans has been synthesized from propargylic alcohols and activated olefins. The reaction is promoted by copper iodide that is removed at the end of the reaction by simple filtration, affording the desired heterocycles in high yield and purity.
Keywords
Solution-phase synthesis , Combinatorial chemistry , Copper catalysis , tetrahydrofurans
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1650908
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