Title of article
A study toward a total synthesis of fostriecin
Author/Authors
Kiyotsuka، نويسنده , , Yohei and Igarashi، نويسنده , , Junji and Kobayashi، نويسنده , , Yuichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
5
From page
2725
To page
2729
Abstract
In order to synthesize the major C(3)C(12) part of fostriecin, asymmetric dihydroxylation of several dienes 5a–f, prepared by cross-coupling reactions of several types, was studied, thus providing high dependency on the hydroxyl groups at C(5) and C(11). The best regioselectivity was obtained with 5d to produce diol 23, which was later transformed into the advanced intermediate 26.
Keywords
coupling reactions , fostriecin , regioselection , Asymmetric dihydroxylation
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651007
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