An approach to oxazolidin-2-ones from the Baylis–Hillman adducts. Formal synthesis of a chloramphenicol derivative

In this communication we describe a straightforward and diastereoselective approach to prepare functionalised oxazolidin-2-ones from Baylis–Hillman adducts. A stereoselective synthesis of a highly substituted vicinal aminoalcohol and a formal synthesis of a chloramphenicol derivative are also described.