Title of article :
Synthesis and biological activity of 3-hydroxy(phosphono)methyl-bearing phosphatidylinositol ether lipid analogues
Author/Authors :
Sun، نويسنده , , Haiying and Bapu Reddy، نويسنده , , Gaddam and George، نويسنده , , Clifford and Meuillet، نويسنده , , Emmanuelle J. and Berggren، نويسنده , , Margareta and Powis، نويسنده , , Garth and Kozikowski، نويسنده , , Alan P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
4
From page :
2835
To page :
2838
Abstract :
Two 3-hydroxy(phosphono)methyl-bearing phosphatidylinositol ether lipid analogues were synthesized and shown to be inhibitors of Akt and PI3-K. These compounds were also shown to inhibit the growth of HT-29 human colon cancer cells and MCF-7 human breast cancer cells.
Journal title :
Tetrahedron Letters
Serial Year :
2002
Journal title :
Tetrahedron Letters
Record number :
1651077
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1651077
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