Title of article
Synthesis of a new chelating agent derived from phenylenediamine for application in radioimmunotherapy
Author/Authors
Gouin، نويسنده , , Sébastien G. and Gestin، نويسنده , , Jean-François and Reliquet، نويسنده , , Alain and Meslin، نويسنده , , Jean Claude and Deniaud، نويسنده , , David، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
3003
To page
3005
Abstract
We report the synthesis of a new diethylenetriaminepentaacetic acid (DTPA) analogue, Ph-DTPA, possessing an aromatic rigid skeleton. This precursor of a bifunctional chelating agent was synthesized by elaboration of the intermediate N-(o-aminophenyl)ethylenediamine and obtained in five steps with an overall yield of 42%. Preliminary complexation studies between Ph-DTPA and 153Sm has been carried out.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651201
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