Title of article
Amination of α,β-unsaturated (2-trimethylsilanylmethyl) carboxylic esters
Author/Authors
Gasperi، نويسنده , , Tecla and Antonietta Loreto، نويسنده , , M and Tardella، نويسنده , , Paolo A and Gambacorta، نويسنده , , Augusto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
3017
To page
3020
Abstract
The reactions of (2-trimethylsilanylmethyl) α,β-unsaturated carboxylic ethyl esters with NsONHCO2Et and CaO produce, after treatment with AcOH, α-methylene N-(ethoxycarbonyl) β-amino carboxylic esters through ring opening and elimination of the trimethylsilyl group from the intermediate aziridine. By ozonization and subsequent reductive cleavage these products give the corresponding N-(ethoxycarbonyl) β-amino α-hydroxy esters.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651215
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