Title of article :
Synthesis of benzyl (6S)-1,3-dichloro-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic derivative
Author/Authors :
Gloanec، نويسنده , , Philippe and Hervé، نويسنده , , Yolande and Brémand، نويسنده , , Nathalie and Lecouvé، نويسنده , , Jean-Pierre and Bréard، نويسنده , , Fabienne and De Nanteuil، نويسنده , , Guillaume، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
We describe the synthesis of benzyl (6S)-1,3-dichloro-4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxylic ester, a new conformationally constrained peptidomimetic derivative. This compound is prepared in seven steps from (S)-pyroglutamic acid as starting material.
Keywords :
Peptidomimetic , 6 , pyroglutamic acid , 4-oxo-4 , 2-a]pyrazine , 7
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters