Author/Authors :
Abell، نويسنده , , Andrew D. and Martyn، نويسنده , , Derek C. and May، نويسنده , , Barnaby C.H. and Nabbs، نويسنده , , Brent K.، نويسنده ,
Abstract :
A method is presented whereby an amino acid is reacted with 5-formyl-1H-pyrrole-2-carboxylic acid to give an N-derivatised tag that has a latent ability to be coloured. A characteristic red pyrrolizin-3-one (coloured tag) is then revealed on treatment with hydrocinnamoyl chloride. This sequence has been carried out on amino acids in solution, and on solid phase, and also on dipeptides.
