• Title of article

    Cyclic RGD peptide by ring-closing metathesis

  • Author/Authors

    Bijani، نويسنده , , Christian and Varray، نويسنده , , Stéphane and Lazaro، نويسنده , , René and Martinez، نويسنده , , Jean and Lamaty، نويسنده , , Frédéric and Kieffer، نويسنده , , Nelly، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    3765
  • To page
    3767
  • Abstract
    A cyclic pseudopeptide containing the RGD sequence has been synthesized in high yield by ring-closing metathesis using a Grubbs’ catalyst in tetrahydrofuran. Conformational analysis has been correlated to structure modeling and preliminary biological activity as an integrin binding inhibitor has been evaluated.
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2002
  • Journal title
    Tetrahedron Letters
  • Record number

    1651742