Title of article
Microwave-assisted Niementowski reaction. Back to the roots
Author/Authors
Alexandre، نويسنده , , François-René and Berecibar، نويسنده , , Amaya and Besson، نويسنده , , Thierry، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
3
From page
3911
To page
3913
Abstract
In a search to speed up an aspect of the drug discovery processes, the Niementowski synthesis of the 3H-quinazolin-4-one core was reinvestigated using microwave irradiation. The experimental methodology and microwave conditions described here are well established, allowing significant rate enhancements and good yields compared to conventional reaction conditions.
Keywords
Niementowski reaction , quinazolin-4-ones , microwave irradiation
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1651851
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