Title of article :
Chemo-, regio- and stereoselective Mitsunobu reaction of unprotected pyrimidine bases with hydroxypyrrolidines
Author/Authors :
Richichi، نويسنده , , Barbara and Cicchi، نويسنده , , Stefano and Chiacchio، نويسنده , , Ugo and Romeo، نويسنده , , Giovanni and Brandi، نويسنده , , Alberto، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
Unprotected pyrimidine bases were used in Mitsunobu reaction to afford in high yield new substituted pyrrolidines. The reaction is chemo-, regio- and stereoselective affording exclusively N-1 alkylated derivatives of (3S)-N-benzyl-3-hydroxypyrrolidine and (3S,4S)-N-benzyl-3,4-dihydroxypyrrolidine.
Keywords :
pyrrolidine , Mitsunobu reaction , Pyrimidine bases
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
