Synthesis of 1′-β-d-glucopyranosyl-1,2,3-triazole-4,5-dimethanol-4,5-bis(isopropylcarbamate) as potential antineoplastic agent

The title compound 5 was prepared from the 1-β-d-azido-glucose 1 via four steps. Alternatively, 5 was synthesized from 1, via acetalation, cycloaddition with acetylene derivative, reduction, then carbamoylation followed by an acid hydrolysis.