Title of article :
A new synthetic approach for novel 4-substituted-5-nitroimidazoles
Author/Authors :
Crozet، نويسنده , , Maxime D. and Perfetti، نويسنده , , Patricia and Kaafarani، نويسنده , , Mustapha and Vanelle، نويسنده , , Patrice and Crozet، نويسنده , , Michel P.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
A new synthetic approach, involving an SRN1 reaction of the anion of 1-methyl-4-phenylsulfonyl-methyl-5-nitro-1H-imidazole with 2,2-dinitropropane and a radical anion or a concerted radical reductive elimination of sulfonyl and nitro groups affords an original 5-nitroimidazole bearing a trisubstituted ethylenic double bond at 4-position.
Keywords :
desulfonylation , 5-Nitroimidazole , C-alkylation , SRN1 reaction , sulfonyl carbanion
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
