Title of article
Ytterbium triflate catalyzed electrophilic substitution of indoles: the synthesis of unnatural tryptophan derivatives
Author/Authors
Janczuk، نويسنده , , Adam and Zhang، نويسنده , , Wei and Xie، نويسنده , , Wenhua and Lou، نويسنده , , Sanzhong and Cheng، نويسنده , , JinPei and Wang، نويسنده , , Peng G. Wang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
4271
To page
4274
Abstract
Benzylamine was combined with ethyl glyoxylate to form the intermediate imine which in the presence of catalytic amount of Yb(OTf)3 underwent electrophilic substitution on the 3-position of a variety of indoles to produce unnatural tryptophan derivatives. Penicillin-G-acylase mediated N-acylation produced optically active tryptophan derivatives.
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652112
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