Author/Authors :
Takechi، نويسنده , , Naoto and A??t-Mohand، نويسنده , , Samia and Médebielle، نويسنده , , Maurice and Dolbier Jr.، نويسنده , , William R.، نويسنده ,
Abstract :
Chemoselective bis-trifluoromethylation of acyl chlorides using the CF3I/TDAE-derived nucleophilic trifluoromethyl anion reagent is reported. Very high yields are obtained of an ester product formed by sequential nucleophilic bis-trifluoromethylation, followed by acylation of the resultant alcoholate.
