Author/Authors :
Fern?ndez، نويسنده , , E. and Garc??a-Ochoa، نويسنده , , S. and Huss، نويسنده , , S. and Mallo، نويسنده , , A. and Bueno، نويسنده , , J.M. and Micheli، نويسنده , , F. and Paio، نويسنده , , A. and Piga، نويسنده , , E. and Zarantonello، نويسنده , , P.، نويسنده ,
Abstract :
Herein we describe a straightforward solid-phase synthesis directed towards the preparation of families of asymmetrically disubstituted furazano[3,4-b]pyrazines by stepwise displacement of the two chlorine atoms in 5,6-dichlorofurazano[3,4-b]pyrazine by nucleophiles. This synthesis has avoided selectivity problems found in solution chemistry.
