Title of article :
Concise asymmetric synthesis of a model compound, (4S,5S,6S)-6-(2,2-dimethoxy)ethyl-4,5-epoxy-6-hydroxy-2-cyclohexenone, for the cyclohexenone core of scyphostatin
Author/Authors :
Fujioka، نويسنده , , Hiromichi and Kotoku، نويسنده , , Naoyuki and Sawama، نويسنده , , Yoshinari and Nagatomi، نويسنده , , Yasushi and Kita *، نويسنده , , Yasuyuki، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
The optically pure cyclohexenone core of scyphostatin (1) has been synthesized from cyclohexadiene acetal 5. The crucial aspects of our synthesis include the intramolecular bromoetherification of 5, the SeO2 oxidation of 7, and the enone formation of 13 to 4 in the final step.
Keywords :
model compound of cyclohexenone core of scyphostatin , cyclohexadiene acetal , asymmetric synthesis , chiral hydrobenzoin
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
