Title of article
Concise asymmetric synthesis of a model compound, (4S,5S,6S)-6-(2,2-dimethoxy)ethyl-4,5-epoxy-6-hydroxy-2-cyclohexenone, for the cyclohexenone core of scyphostatin
Author/Authors
Fujioka، نويسنده , , Hiromichi and Kotoku، نويسنده , , Naoyuki and Sawama، نويسنده , , Yoshinari and Nagatomi، نويسنده , , Yasushi and Kita *، نويسنده , , Yasuyuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
4825
To page
4828
Abstract
The optically pure cyclohexenone core of scyphostatin (1) has been synthesized from cyclohexadiene acetal 5. The crucial aspects of our synthesis include the intramolecular bromoetherification of 5, the SeO2 oxidation of 7, and the enone formation of 13 to 4 in the final step.
Keywords
model compound of cyclohexenone core of scyphostatin , cyclohexadiene acetal , asymmetric synthesis , chiral hydrobenzoin
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1652480
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