Author/Authors :
Volkmann، نويسنده , , Carla J. and Chateauneuf، نويسنده , , Ginger M. and Pradhan، نويسنده , , Jyotsna and Bauman، نويسنده , , Andrew T. and Brown، نويسنده , , Richard E. and Murthy، نويسنده , , Pushpalatha P.N. Murthy، نويسنده ,
Abstract :
Dynamic NMR and molecular modeling techniques were employed to investigate the influence of structural characteristics on the ring inversion processes of inositol phosphates. The results indicate that inositol phosphates that contain the syn-1,3,5-triaxial trisphosphate arrangement show great proclivity to adopt the sterically hindered conformation. These results suggest that the ability to form chelation cages with counter-ions is a major factor in the ring inversion processes of inositol phosphates.
