Author/Authors :
Hegde، نويسنده , , Vinod R and Puar، نويسنده , , Mohindar S and Dai، نويسنده , , Ping and Patel، نويسنده , , Mahesh and Gullo، نويسنده , , Vincent P and Pramanik، نويسنده , , Birendra and Jenh، نويسنده , , Chung-Her، نويسنده ,
Abstract :
The organic extract of the fermentation broth of a Streptomycete microorganism was found to contain SCH 212394 (1), a condensed aromatic peptide. The structure was established by extensive NMR spectral data and derivatization. SCH 212394 (1), inhibited CD28–CD80 costimulation with an IC50 of 1.25 μM.
