Author/Authors :
Haldar، نويسنده , , Debasish and Maji، نويسنده , , Samir Kumar and Drew، نويسنده , , Michael G.B. and Banerjee، نويسنده , , Arijit and Banerjee، نويسنده , , Arindam، نويسنده ,
Abstract :
The single-crystal X-ray diffraction study of a terminally protected tetrapeptide Boc-Leu-Aib-Phe-Aib-OMe 1 (Aib: α-amino-isobutyric acid) reveals that it forms a continuous hydrogen-bonded supramolecular helix starting from the double bend conformation as an associating sub-unit. The scanning electron micrograph of the peptide 1 exhibits amyloid-like fibrils in the solid state.