Author/Authors :
Mitchell، نويسنده , , Michael L and Lee، نويسنده , , Lac V and Wong، نويسنده , , Chi-Huey، نويسنده ,
Abstract :
Fructose-diphosphate aldolase was employed in the chemoenzymatic synthesis of six-membered GDP-iminocyclitols. These compounds were evaluated for activity against α-1,3-fucosyltransferases and found to be potent inhibitors.
