Title of article :
Solid-phase access to polyhydroxypyrrolizidines by 1,3-dipolar cycloaddition of (S)-3-alkoxypyrroline N-oxide to maleate and crotonate derivatives
Author/Authors :
Pisaneschi، نويسنده , , Federica and Della Monica، نويسنده , , Carmela and Cordero، نويسنده , , Franca M and Brandi، نويسنده , , Alberto، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
2,7-Dihydroxyhexahydropyrrolizine-1-carboxylic acid derivatives have been prepared in solid-phase by intermolecular 1,3-dipolar cycloaddition between an immobilised maleate or 4-hydroxycrotonate and an enantiopure 3-alkoxypyrroline N-oxide.
Keywords :
Pyrrolizidines , 3-dipolar cycloaddition , 1 , nitrone , solid-phase synthesis
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
