Title of article :
Microwave-assisted solid-phase synthesis (MASS) of 2,6,9-trisubstituted purines
Author/Authors :
Austin، نويسنده , , Richard E. and Okonya، نويسنده , , John F. and Bond، نويسنده , , Daniel R.S. and Al-Obeidi، نويسنده , , Fahad، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Abstract :
In an attempt to discover a high-throughput method for the synthesis of 2,6,9-trisubstituted purines, it was found that microwave irradiation was beneficial in accelerating the nucleophilic displacement of halogens by amines at the C-2 position of the purine nucleus. A method for microwave-assisted solid-phase synthesis (MASS) of 2,6,9-trisubstituted purines is presented.
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
