Author/Authors :
Kim، نويسنده , , Jong Han and Kim، نويسنده , , Hae-Kyung and Jeon، نويسنده , , Sun Bok and Son، نويسنده , , Kwang-Hee and Kim، نويسنده , , Eun Hee and Kang، نويسنده , , Sung Kwon and Sung، نويسنده , , Nack-Do and Kwon، نويسنده , , Byoung-Mog Kwon، نويسنده ,
Abstract :
A new sesquiterpene–monoterpene lactone, artemisolide, was isolated from the aerial parts of Artemisia argyi. The structure of artemisolide was elucidated by spectroscopic data including HMBC and NOESY. The structure was confirmed by X-ray crystallographic analysis. Artemisolide exhibited in vitro cytotoxic activity with GI50 values of 2–8 μM against cancer cell lines.