Title of article
Regio- and stereoselective synthesis of the major metabolite of quercetin, quercetin-3-O-β-d-glucuronide
Author/Authors
Mohamed Bouktaib، نويسنده , , Mohamed and Atmani، نويسنده , , Aziz and Rolando، نويسنده , , Christian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
4
From page
6263
To page
6266
Abstract
Protected quercetin was first transformed selectively in its 3-O-β-d-glucoside. Further protection of the remaining phenolic hydroxyl group allows a clean oxidation of the glucoside by TEMPO/NaOCl/NaBr under phase transfer conditions into the corresponding glucuronide which was cleanly deprotected to quercetin-3-O-β-d-glucuronide.
Keywords
Quercetin , O-glucoside , TEMPO oxidation , O-Glucuronide , chemical synthesis
Journal title
Tetrahedron Letters
Serial Year
2002
Journal title
Tetrahedron Letters
Record number
1653455
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