Synthèse chimiosélective des benzimidazoles sur silice traitée par le chlorure du thionyle

Chemoselective synthesis of benzimidazoles in good yield was achieved with a variety of aldehydes in heterogeneous media. This efficient procedure has been developed for the condensation of ortho-phenylene-diamine with aldehydes by silica-supported thionyl chloride in dichloromethane at ambient temperature.