• Title of article

    Rapid access to cis 3-substituted prolines

  • Author/Authors

    Pellegrini، نويسنده , , Nadia and Schmitt، نويسنده , , Martine and Bourguignon، نويسنده , , Jean-Jacques، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2003
  • Pages
    2
  • From page
    6779
  • To page
    6780
  • Abstract
    The O-triflate of 2-cyano-3-oxopyrrolidine was obtained and used in a palladium coupling reaction. The resulting Δ2-pyrrolidine derivatives allowed diastereocontrol at C2 and C3 after catalytic hydrogenation and led to chiral 3-substituted prolines as conformationally constrained amino acids.
  • Keywords
    prolines , Pd coupling , Peptidomimetics
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2003
  • Journal title
    Tetrahedron Letters
  • Record number

    1654313