Title of article :
Metal oxide in aqueous organic solution promoted chemoselective N-sulfonylation of hydrophilic amino alcohols
Author/Authors :
Kang، نويسنده , , Hak Hee and Rho، نويسنده , , Ho Sik and Kim، نويسنده , , Duck Hee and Oh، نويسنده , , Seong-Geun، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
The reaction of hydrophilic amino alcohols with sulfonyl chlorides in the presence of metal oxide (MgO, CuO, Ag2O) in aqueous organic solution cleanly provided alkanolsulfonamide. Advantages of this method were mild, neutral reaction conditions, chemoselectivity and easy isolation of the final product.
Keywords :
amino alcohols , Sulfonamide , sulfonyl chloride , aqueous organic solution , metal oxide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
